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dc.date.accessioned 2012-05-16T20:05:58Z
dc.date.available 2012-05-16T20:05:58Z
dc.date.issued 2012
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/18127
dc.description.abstract The solid-state characterization, dimorphic nature, solubility and solvent-mediated transformation of the anhydrous form and the monohydrate form of L-phenylalanine have been firstly conducted in detail. The results have shown that, the two forms are enantiotropically related, and the transformation rate can be prohibited by increasing temperature and reducing water content in the solvent mixtures. These results will contribute to a better understanding about the pseudopolymorphic systems for pharmaceutical industry. es
dc.format.extent 292-297 es
dc.language en es
dc.subject Farmacología es
dc.subject active pharmaceutical ingredients; characterization; phenylalanine; pseudopolymorphism; transformation es
dc.subject Aminoácidos es
dc.subject Fenilalanina es
dc.title Pseudopolymorphism of Active Pharmaceutical Ingredients (APIs): A Case Study of L-Phenylalanine es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/31/2/LAJOP_31_2_1_18.pdf es
sedici.identifier.issn 0326-2383 es
sedici.creator.person Lu, Jie es
sedici.creator.person Liu, Zhen es
sedici.creator.person Wang, Jing es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Articulo es
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Latin American Journal of Pharmacy
sedici.relation.journalVolumeAndIssue vol. 31, no. 02


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