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dc.date.accessioned 2009-06-22T14:14:04Z
dc.date.available 2009-06-22T03:00:00Z
dc.date.issued 2009
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/7742
dc.description.abstract The use of two alternative vegetable oils (grape seed oil and almond kernel oil) to prepare nanoparticulated delivery systems (nanocapsules and nanoemulsions) for active substances was evaluated. They were prepared by interfacial deposition of preformed polymer (poly-ε-caprolactone) or spontaneous emulsification, respectively. All formulations presented nanometric size, polydispersity index below 0.30, negative zeta potential and spherical-shaped particles. Benzophenone-3, as a model substance was efficiently entrapped in these systems, independent on the type of oily phase. Its association did not alter significantly the physicochemical properties of the nanoparticle dispersions, which remained adequate until 6 months of storage. Nanocapsules and nanoemulsions prepared with both vegetable oils were suitable to delay benzophenone-3 photodegradation under UV radiation. es
dc.format.extent 165-172 es
dc.language en es
dc.subject Preparaciones Farmacéuticas es
dc.subject aceite vegetal es
dc.subject almond kernel oil; grape seed oil; nanoparticles es
dc.title Oil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/trabajos/28/2/LAJOP_28_2_1_1_599ZY133S8.pdf es
sedici.creator.person Almeida, Juliana S. es
sedici.creator.person Jezur, Luciane es
sedici.creator.person Fontana, Marcia C. es
sedici.creator.person Paese, Karina es
sedici.creator.person Silva, Cristiane B. es
sedici.creator.person Pohlmann, Adriana Raffin es
sedici.creator.person Guterres, Sílvia Stanisçuaski es
sedici.creator.person Beck, Ruy Carlos Ruver es
sedici.subject.materias Farmacia es
sedici.description.fulltext true es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Articulo es
sedici.description.peerReview peer-review es
sedici2003.identifier ARG-FARM-ART-0000001228 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 28, no. 2 es


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