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dc.date.accessioned | 2011-01-06T14:04:20Z | |
dc.date.available | 2011-01-06T03:00:00Z | |
dc.date.issued | 2010 | es |
dc.identifier.uri | http://sedici.unlp.edu.ar/handle/10915/8085 | |
dc.description.abstract | Ferula hermonis (Apiaceae) is a well known Middle-Eastern medicinal plant. It has long been used traditionally as an aphrodisiac agent. The antinociceptive and anti-inflammatory activities of the root oil of F. hermonis were evaluated by the hot-plate test, the acetic acid-induced writhing test and the carragennan-induced rat paw edema test. In the hot-plate test, the root oil in oral doses of 400 and 800 mg/kg significantly increased the reaction time of animals to thermal pain, and in the acetic acid-induced writhing test, in similar oral doses it showed a considerable inhibition of acetic acid-induced writhing in mice in a dose-dependant manner. In the carrageenan induced paw oedema model, the oral administration of 50 and 100 mg/kg of F. hermonis root oil to adult Wister rats showed a statistically significant decrease in rat paw o induced by carrageenan 1 and 2 h after carrageenan injection. | es |
dc.format.extent | 1436-1439 | es |
dc.language | en | es |
dc.subject | anti-inflammatory; antinociceptive; apiaceae; carrageenan-induced edema; ferula hermonis; hot plate test | es |
dc.title | Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals | es |
dc.type | Articulo | es |
sedici.identifier.uri | http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_2.pdf | es |
sedici.creator.person | Geroushi, Afaf | es |
sedici.creator.person | Auzi, Abdurazag A. | es |
sedici.creator.person | Elhwuegi, Abdalla S. | es |
sedici.creator.person | Elzawam, Fawzi | es |
sedici.creator.person | El-Sherif, Akram | es |
sedici.creator.person | Nahar, Lutfun | es |
sedici.creator.person | Sarker, Satyajit D. | es |
sedici.subject.materias | Farmacia | es |
sedici.description.fulltext | false | es |
mods.originInfo.place | Colegio de Farmacéuticos de la Provincia de Buenos Aires | es |
sedici.subtype | Comunicacion | es |
sedici2003.identifier | ARG-FARM-ART-0000001572 | es |
sedici.relation.journalTitle | Latin American Journal of Pharmacy | es |
sedici.relation.journalVolumeAndIssue | vol. 29, no. 8 | es |