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dc.date.accessioned | 2011-03-31T19:14:54Z | |
dc.date.available | 2011-03-31T03:00:00Z | |
dc.date.issued | 2011 | es |
dc.identifier.uri | http://sedici.unlp.edu.ar/handle/10915/8126 | |
dc.description.abstract | The flavonoid 2''-O-rhamnosylswertisin in Aleurites moluccana is related to the therapeutic effect of the plant, making it an adequate marker. In this work a method of total flavonoid assay was developed and validated, expressed in its marker. A double reflux of dried extract obtained from A. moluccana leaves (0.4 g) with 50 % (v/v) ethanol was carried out. After filtration, the solution was complexed with 2 % AlCl3 in 50 % (v/v) ethanol, and the absorbance read at 397 nm after 90 min. The number of refluxes (1-2), volume of complexing agent (0.5-3 mL), stability of complexing agent and complexation time (15-120 min) were evaluated. The specific absorption coefficient (E1%1cm) of the marker compound was 77.18. The method showed linearity (r2 > 0.99) at the tested range, good precision (RSD % ≈ 5 %, intra-day and inter-days) and accuracy of 99.3 %. The dried extract of leaves of A. moluccana showed 0.15 % total flavonoids, expressed in 2''-O-rhamnosylswertisin. | es |
dc.format.extent | 213-219 | es |
dc.language | en | es |
dc.subject | Aleurites moluccana; analytical validation; flavonoid complexation; total flavonoids | es |
dc.subject | Plantas Medicinales | es |
dc.subject | Flavonoides | es |
dc.subject | Técnicas y Procedimientos de Laboratorio | es |
dc.title | Assay of total flavonoids in dried extract of Aleurites moluccana | es |
dc.type | Articulo | es |
sedici.identifier.uri | http://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_1_1.pdf | es |
sedici.creator.person | Cechinel Filho, Valdir | es |
sedici.creator.person | Silva, Ruth M L. | es |
sedici.creator.person | Meyre Silva, Christiane | es |
sedici.creator.person | Matos, Denise C.S. | es |
sedici.creator.person | Bresolin, Tania M.B. | es |
sedici.subject.materias | Farmacia | es |
sedici.description.fulltext | false | es |
mods.originInfo.place | Colegio de Farmacéuticos de la Provincia de Buenos Aires | es |
sedici.subtype | Articulo | es |
sedici.description.peerReview | peer-review | es |
sedici2003.identifier | ARG-FARM-ART-0000001613 | es |
sedici.relation.journalTitle | Latin American Journal of Pharmacy | es |
sedici.relation.journalVolumeAndIssue | vol. 30, no. 2 | es |