Subir material

Suba sus trabajos a SEDICI, para mejorar notoriamente su visibilidad e impacto

 

Mostrar el registro sencillo del ítem

dc.date.accessioned 2012-03-28T11:31:17Z
dc.date.available 2012-03-28T03:00:00Z
dc.date.issued 2012 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8424
dc.description.abstract Cefoperazone complexes with different metal ions of 1:1 metal to antibiotic stoichiometry have been prepared. The [M(cefopz)CI] complexes (M = Co, Cu and Cd) were characterized by physicochemical and spectroscopic methods. The solubility of the cefoperazone complexes in water and common organic solvents is reduced on complexation. All complexes show higher activity against Salmonella enteritidis. The Co(II) and Cd(II) complexes show better activity in the case of Pseudomonas aeruginosa and Escherichia coli, and Cu(II) and Cd(II) complexes against Shigella sonnei than cefoperazone sodium. The complexes showed to be less active than free cefoperazone against Staphylococcus aureus and Proteus mirabilis. es
dc.description.abstract Cefoperazone complexes with different metal ions of 1:1 metal to antibiotic stoichiometry have been prepared. The [M(cefopz)Cl] complexes (M = Co, Cu and Cd) were characterized by physicochemical and spectroscopic methods. The solubility of the cefoperazone complexes in water and common organic solvents is reduced on complexation. All complexes show higher activity against Salmonella enteritidis. The Co(II) and Cd(II) complexes show better activity in the case of Pseudomonas aeruginosa and Escherichia coli, and Cu(II) and Cd(II) complexes against Shigella sonnei than cefoperazone sodium. The complexes showed to be less active than free cefoperazone against Staphylococcus aureus and Proteus mirabilis. en
dc.format.extent 27-31 es
dc.language en es
dc.subject Metales es
dc.subject antibiótico es
dc.subject Cefoperazona es
dc.subject Agentes Antibacterianos es
dc.title Antibacterial activity of cefoperazone metal complexes es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_1_4.pdf es
sedici.creator.person Lopez, María E. es
sedici.creator.person Bravo, Alina es
sedici.creator.person Anacona, Juan R. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Articulo es
sedici.description.peerReview peer-review es
sedici2003.identifier ARG-FARM-ART-0000001912 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 31, no. 1 es


Descargar archivos

Thumbnail
Resumen
Descargar archivo (36.81Kb) - PDF
Icon
Enlace externo

Este ítem aparece en la(s) siguiente(s) colección(ones)