The saponified petroleum ether extract (SPE) of the Annona reticulata L. bark were studied
for fatty acid composition by GC-MS analysis. Six fatty acids amounting 86.68% of the total contents were
identified. The composition of saturated and unsaturated fatty acid was 22.10 % and 64.58 %, respectively.
SPE at the doses of 12.5, 25 and 50 mg/kg body weight showed significant central as well as peripheral
analgesic, along with anti-inflammatory activity.