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dc.date.accessioned 2011-12-01T13:32:28Z
dc.date.available 2011-12-01T03:00:00Z
dc.date.issued 2011 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8356
dc.description.abstract A short synthetic approach allowed the preparation, in two steps, of (3S,4R)- and (3R,4R)-2- methylene-3-hydroxy-4-(hydroxymethyl)-γ-butyrolactones from 2,3-O-(3-pentylidene)-D-glyceraldehyde, with overall yields of 32 % and 9 %, respectively. The structure of these γ-butyrolactones was revised by experimental and theoretical investigations. es
dc.format.extent 1661-1664 es
dc.language en es
dc.subject antitumoral agents; BLYP/6-31G* theoretical calculation; γ-butyrolactones es
dc.title Short and stereoselective synthesis of α-methylene-β-hydroxy-γ-butyrolactone diastereomers es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/30/8/LAJOP_30_8_2_8.pdf es
sedici.title.subtitle Structures revised by theoretical investigations es
sedici.creator.person Díaz, Gaspar es
sedici.creator.person Carvalho, Gláucia S. es
sedici.creator.person Soares, Flávia R. F. es
sedici.creator.person Alcântara, Antônio F. de C. es
sedici.creator.person Diaz, Marisa A. N. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001843 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 30, no. 8 es


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