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dc.date.accessioned | 2011-12-01T13:32:28Z | |
dc.date.available | 2011-12-01T03:00:00Z | |
dc.date.issued | 2011 | es |
dc.identifier.uri | http://sedici.unlp.edu.ar/handle/10915/8356 | |
dc.description.abstract | A short synthetic approach allowed the preparation, in two steps, of (3S,4R)- and (3R,4R)-2- methylene-3-hydroxy-4-(hydroxymethyl)-γ-butyrolactones from 2,3-O-(3-pentylidene)-D-glyceraldehyde, with overall yields of 32 % and 9 %, respectively. The structure of these γ-butyrolactones was revised by experimental and theoretical investigations. | es |
dc.format.extent | 1661-1664 | es |
dc.language | en | es |
dc.subject | antitumoral agents; BLYP/6-31G* theoretical calculation; γ-butyrolactones | es |
dc.title | Short and stereoselective synthesis of α-methylene-β-hydroxy-γ-butyrolactone diastereomers | es |
dc.type | Articulo | es |
sedici.identifier.uri | http://www.latamjpharm.org/resumenes/30/8/LAJOP_30_8_2_8.pdf | es |
sedici.title.subtitle | Structures revised by theoretical investigations | es |
sedici.creator.person | Díaz, Gaspar | es |
sedici.creator.person | Carvalho, Gláucia S. | es |
sedici.creator.person | Soares, Flávia R. F. | es |
sedici.creator.person | Alcântara, Antônio F. de C. | es |
sedici.creator.person | Diaz, Marisa A. N. | es |
sedici.subject.materias | Farmacia | es |
sedici.description.fulltext | false | es |
mods.originInfo.place | Colegio de Farmacéuticos de la Provincia de Buenos Aires | es |
sedici.subtype | Comunicacion | es |
sedici2003.identifier | ARG-FARM-ART-0000001843 | es |
sedici.relation.journalTitle | Latin American Journal of Pharmacy | es |
sedici.relation.journalVolumeAndIssue | vol. 30, no. 8 | es |