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dc.date.accessioned 2020-08-04T14:02:25Z
dc.date.available 2020-08-04T14:02:25Z
dc.date.issued 2016-12
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/101282
dc.description.abstract Small Bowel transplantation in rats is a highly complex microsurgical procedure because several technical complications may lead to recipient mortality and transplant failure. Our aim was to report the most common complications associated with orthotopic and heterotopic intestinal transplantation in rats in order to identify the “pitfalls” of the procedure and prevent them. A retrospective multicenter study was performed. All participant centers have established rodent transplant procedures and trained surgeons. Two hundred ninety-three complications from 264 unsuccessful intestinal transplants were reported, representing an overall failure rate of 15% of the procedures performed. Recipient complications were most frequent than donor (257 vs. 36 p<0.0001). Excessive surgical time (11/36); severe hemorrhage (12/36) and inappropriate infusion of the preservation solution in the intestinal graft (11/36) were the most common donor complications. Arterial anastomosis bleeding (50/257), venous anastomosis bleeding (35/257) and portal vein stenosis (26/257) were the most common intraoperative complications in the recipient. To maximize success rate, surgeons should optimize time and avoid bleeding during graft dissection in the donor surgery. After performing a bloodless vascular anastomosis an adequate post-operative management of the animal is mandatory to guarantee survival. en
dc.language en es
dc.subject Intestinal transplantation es
dc.subject Surgical compliations es
dc.subject Rats es
dc.subject Microsurgery es
dc.title Small bowel transplantation in rats, a multicenter experience summarizing the pitfalls to be overcome en
dc.type Articulo es
sedici.identifier.uri https://ri.conicet.gov.ar/11336/48434 es
sedici.identifier.uri http://www.oatext.com/Small-bowel-transplantation-in-rats,-A-multicenter-experience-summarizing-the-pitfalls-to-be-overcome.php es
sedici.identifier.other http://dx.doi.org/10.15761/TiT.1000217 es
sedici.identifier.other hdl:11336/48434 es
sedici.identifier.issn 2399-5289 es
sedici.creator.person Stringa, Pablo Luis es
sedici.creator.person Andrés Moreno, Ane M. es
sedici.creator.person Lausada, Natalia Raquel es
sedici.creator.person Pastor Oliver, Cristina es
sedici.creator.person Abate, Juan Cruz es
sedici.creator.person Vecchio Dezillio, Leandro Emmanuel es
sedici.creator.person Rumbo, Martín es
sedici.creator.person Navarro Zorraquino, Marta es
sedici.creator.person Hernández Oliveros, Francisco es
sedici.creator.person Gondolesi, Gabriel Eduardo es
sedici.subject.materias Medicina es
sedici.subject.materias Ciencias Exactas es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ciencias Médicas es
mods.originInfo.place Laboratorio y Programa de Trasplante de Organos, Tejidos y Células es
mods.originInfo.place Instituto de Estudios Inmunológicos y Fisiopatológicos es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Trends in Transplantation es
sedici.relation.journalVolumeAndIssue vol. 10, no. 1 es


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