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dc.date.accessioned 2020-08-06T18:02:33Z
dc.date.available 2020-08-06T18:02:33Z
dc.date.issued 2015-07
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/101564
dc.description.abstract We studied the index of DNA synthesis (DNAs) of two cellular carcinomas: the hepatocellular ES12a and the mammary TN60 of mice, throughout one circadian cycle. In the results, we observed that both tumors have circadian rhythms (CRs), but the peaks of DNAs vary. Besides, the mean of DNAs along 24 h shows significative differences, the TN60 has higher values than the ES12a. These observed CR in the DNAs index in both carcinomas mean that, at least in partly, the proliferation of cancer cells can be regulated by endocrine factor as it normally occurs in ordinary cells. The big problem we can find for the chronopharmacology is that it is impossible to know in advance the rate of proliferation of each tumor. en
dc.format.extent 573-578 es
dc.language en es
dc.subject Carcinoma es
dc.subject Circadian rhythms es
dc.subject DNA synthesis es
dc.subject Mice es
dc.title Circadian rhythms of proliferation events in two mouse carcinomas en
dc.type Articulo es
sedici.identifier.uri https://ri.conicet.gov.ar/11336/38465 es
sedici.identifier.other http://dx.doi.org/10.1080/09291016.2015.1034971 es
sedici.identifier.other hdl:11336/38465 es
sedici.identifier.issn 0929-1016 es
sedici.creator.person García, Marcela Nilda es
sedici.creator.person Andrini, Laura Beatriz es
sedici.creator.person Martínez, Marina es
sedici.creator.person Inda, Ana María es
sedici.creator.person Palma, María Belén es
sedici.creator.person Miriuka, Santiago Gabriel es
sedici.creator.person Errecalde, Ana Lía es
sedici.subject.materias Ciencias Médicas es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ciencias Médicas es
mods.originInfo.place Comisión de Investigaciones Científicas de la provincia de Buenos Aires es
sedici.subtype Preprint es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Biological Rhythm Research es
sedici.relation.journalVolumeAndIssue vol. 46, no. 4 es


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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)