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dc.date.accessioned 2020-09-15T14:18:51Z
dc.date.available 2020-09-15T14:18:51Z
dc.date.issued 2010-11
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/104650
dc.description.abstract Phospholamban (PLN) is a small sarcoplasmic reticulum (SR) protein that in the dephosphorylated state tonically inhibits the SR Ca2+-ATPase (SERCA2a). Different type of evidence to be described, points to PLN as a crucial regulator of basal cardiac Ca2+ cycling, contractility and relaxation and as a main determinant of β -adrenergic stimulatory responses in vivo. The involvement of PLN and PLN phosphorylation under pathological conditions will be also discussed. en
dc.format.extent 8-17 es
dc.language en es
dc.subject Phospholamban es
dc.subject Cardiac relaxation es
dc.subject Contractility es
dc.title Phospholamban: a tiny protein with a prominent role in the regulation of cardiac relaxation and contractility en
dc.type Articulo es
sedici.identifier.uri http://hdl.handle.net/11336/61840 es
sedici.identifier.other hdl:11336/61840 es
sedici.identifier.issn 1669-5410 es
sedici.creator.person Mattiazzi, Alicia Ramona es
sedici.creator.person Mundiña-Weilenmann, Cecilia es
sedici.creator.person Vittone, Leticia es
sedici.subject.materias Ciencias Médicas es
sedici.description.fulltext true es
mods.originInfo.place Centro de Investigaciones Cardiovasculares es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Physiological Mini Reviews es
sedici.relation.journalVolumeAndIssue vol. 5, no. 3 es


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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)