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dc.date.accessioned 2020-09-16T13:50:24Z
dc.date.available 2020-09-16T13:50:24Z
dc.date.issued 2015
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/104747
dc.description.abstract The cytotoxicity activity of the recently reported [VO(H2O)2(SO4)dppz]·2H2O complex (dppz = dipyrido[3,2-a:2',3'- c]phenazine) on MG-63 human osteosarcoma cell line was investigated. It was found that it caused a concentration related inhibitory effect in the concentration range between 5 and 25 µM and diminished the cell viability ca. 40% in the range from 25 to 100 µM, without dose/response effects in this range. These biological effects are, in general, similar to those previously reported for the related [VO(ODA)dppz]·3H2O (ODA = dianion of oxodiacetic acid) and [VO(ODA)(phen)]·1.5H2O (phen = o- phenanthroline) complexes. The importance of the presence of DNAintercalating ligands in these complexes is emphasized. en
dc.format.extent 465-468 es
dc.language en es
dc.subject oxidovanadium(IV) es
dc.subject dipyrido[3,2-a:2',3'-c]phenazine (dppz) es
dc.subject metallointercalators es
dc.subject human osteosarcoma cell line es
dc.title Cytotoxicity action of an oxidovanadium(IV)-DPPZ complex on MG-63 human osteosarcoma cell line en
dc.type Articulo es
sedici.identifier.uri http://hdl.handle.net/11336/50200 es
sedici.identifier.uri https://www.tsijournals.com/abstract/cytotoxicity-action-of-an-oxidovanadiumivdppz-complex-on-mg63-human-osteosarcoma-cell-line-2208.html es
sedici.identifier.other hdl:11336/50200 es
sedici.identifier.issn 0974-7435 es
sedici.creator.person León, Ignacio Esteban es
sedici.creator.person Etcheverry, Susana Beatriz es
sedici.creator.person Baran, Enrique José es
sedici.subject.materias Ciencias Exactas es
sedici.subject.materias Química es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ciencias Exactas es
mods.originInfo.place Centro de Química Inorgánica es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle BioTechnology: An Indian Journal es
sedici.relation.journalVolumeAndIssue vol. 11, no. 12 es


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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)