Upload resources

Upload your works to SEDICI to increase its visibility and improve its impact


Show simple item record

dc.date.accessioned 2020-09-18T16:45:18Z
dc.date.available 2020-09-18T16:45:18Z
dc.date.issued 2017
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/104962
dc.description.abstract 2,1-Benzisoxazoles have been selectively synthesized through reductive heterocyclization of 2-nitroacylarenes using Pt-supported nanoparticles. The reaction involves a cascade process in which the first step is the reduction of the nitro group into hydroxylamine followed by heterocyclization through the nucleophilic attack of the hydroxylamine group to the carbonyl of the acyl group and further dehydration. The reaction was performed on Pt/C, Pt/TiO₂, and Pt/MgO using hydrogen as the reducing agent under mild reaction conditions. The results showed that Pt/MgO was the most active and selective catalyst. The study of the influence of the crystal size of the metal on the activity and selectivity, combined with the reaction mechanism examined by in situ Fourier transform infrared spectroscopy of the adsorbed reactant, showed that the maximum activity and selectivity to the target compound can be achieved by controlling the architecture of metal particles and acid–base properties of the support. The effect of temperature on selectivity, the stability of the Pt/MgO catalyst, and the scope of the reaction have been studied. Finally, reductive heterocyclization using different metals (Pd and Au) supported on MgO has also been performed. en
dc.format.extent 8255-8262 es
dc.language en es
dc.subject Reductive heterocyclization es
dc.subject 2,1-benzisoxazole es
dc.subject Pt/MgO es
dc.subject 2-nitroacylarenes es
dc.subject Cascade process es
dc.title Chemoselective Reductive Heterocyclization by Controlling the Binomial Architecture of Metal Particles and Acid−Base Properties of the Support en
dc.type Articulo es
sedici.identifier.other https://doi.org/10.1021/acscatal.7b01841 es
sedici.identifier.issn 2155-5435 es
sedici.creator.person Marti, L. es
sedici.creator.person Sánchez, Laura Mabel es
sedici.creator.person Climent, María J. es
sedici.creator.person Corma, A. es
sedici.creator.person Iborra, S. es
sedici.creator.person Romanelli, Gustavo Pablo es
sedici.creator.person Concepcion, P. es
sedici.subject.materias Ciencias Exactas es
sedici.subject.materias Química es
sedici.description.fulltext true es
mods.originInfo.place Centro de Investigación y Desarrollo en Ciencias Aplicadas es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution 4.0 International (CC BY 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle ACS Catalysis es
sedici.relation.journalVolumeAndIssue vol. 7, no. 12 es

Download Files

This item appears in the following Collection(s)

Creative Commons Attribution 4.0 International (CC BY 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution 4.0 International (CC BY 4.0)