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dc.date.accessioned 2020-10-05T20:01:59Z
dc.date.available 2020-10-05T20:01:59Z
dc.date.issued 2017
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/106189
dc.description.abstract Helminth infections are widespread in the poultry industry. There is evidence of extra-label use of some drugs, such as ivermectin (IVM), in broiler poultry. Pharmacokinetic and residual studies of IVM in poultry, however, are rather scarce. Our aim was to determine time restrictions for broiler chickens fed with balanced feed mixed with IVM for 21 days, and thus achieve acceptable residual levels for consumption as established by the European Union. Sixty 1-day-old chicks were fed with food supplemented with IVM at 5 mg kg–1 feed for 21 days. Groups of six treated animals were sacrificed at 0, 1, 2, 4, 8, 10, 15, 20 and 28 days after treatment. Liver, skin/fat, kidney and muscle samples were obtained. IVM were determined by liquid chromatography with fluorescence detection after automatic solid-phase extraction with SPE C18 cartridges. The highest concentrations were measured in the liver, which is logical given that IVM is a drug that undergoes extensive hepatic metabolism. The optimal withdrawal time for edible tissues of these animals to stay within the permitted residual levels were: 12 days for liver, 8 days for skin/fat, 0 days for muscle and 10 days for kidney. en
dc.format.extent 624-631 es
dc.language en es
dc.subject endectocide es
dc.subject ivermectin es
dc.subject chicken es
dc.subject residues es
dc.subject withdrawal time es
dc.title Residue depletion of ivermectin in broiler poultry en
dc.type Articulo es
sedici.identifier.uri https://www.tandfonline.com/doi/full/10.1080/19440049.2016.1278307 es
sedici.identifier.other http://dx.doi.org/10.1080/19440049.2016.1278307 es
sedici.identifier.issn 1944-0057 es
sedici.creator.person Mestorino, Olga Nora es
sedici.creator.person Buldain, Daniel Cornelio es
sedici.creator.person Buchamer, Andrea Verónica es
sedici.creator.person Gortari Castillo, Lihuel es
sedici.creator.person Daniele, Martín Rafael es
sedici.creator.person Marchetti, María Laura es
sedici.subject.materias Veterinaria es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ciencias Veterinarias es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Food Additives & Contaminants: Part A es
sedici.relation.journalVolumeAndIssue vol. 34, no. 4 es


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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)