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dc.date.accessioned 2021-09-27T14:39:58Z
dc.date.available 2021-09-27T14:39:58Z
dc.date.issued 2017-02
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/125649
dc.description.abstract Primary cilia are microtubule based organelles that sense and transduce multiple extracellular signals to the interior of the cell through several signaling pathways. Ciliary defects lead to different pathologies. Interestingly, decreased ciliary expression has been associated with different types of cancer. In this review, we discuss the function and dynamics of primary cilia, their relation to different diseases and in particular their role in cancer, and how they can be explored as potential therapeutic targets. en
dc.format.extent 1-11 es
dc.language en es
dc.subject Primary cilia es
dc.subject Cholangiocarcinoma es
dc.subject Cancer es
dc.subject HDAC6 es
dc.title The role of primary cilia in cancer en
dc.type Articulo es
sedici.identifier.uri https://pmr.safisiol.org.ar/archive/id/93 es
sedici.identifier.issn 1669-5410 es
sedici.creator.person Peixoto, Estanislao es
sedici.creator.person Mansini, Adrian P. es
sedici.creator.person Thelen, Kristen M. es
sedici.creator.person Gaspari, Cesar I. es
sedici.creator.person Jin, Sujeong es
sedici.creator.person Gradilone, Sergio A. es
sedici.subject.materias Biología es
sedici.subject.materias Ciencias Médicas es
sedici.description.fulltext true es
mods.originInfo.place Sociedad Argentina de Fisiología es
sedici.subtype Revision es
sedici.rights.license Creative Commons Attribution 4.0 International (CC BY 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Physiological Mini Reviews es
sedici.relation.journalVolumeAndIssue vol. 10, no. 1 es


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Creative Commons Attribution 4.0 International (CC BY 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution 4.0 International (CC BY 4.0)