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dc.date.accessioned 2021-12-09T13:19:54Z
dc.date.available 2021-12-09T13:19:54Z
dc.date.issued 2011
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/129304
dc.description.abstract As a common laboratory practice, rats are studied as biological models for understanding human physiology. Even though, with the advent of modern computer sciences, new methodologies appeared in medical sciences like simulation and optimization to simplify and improve the experimental work. With this background, a novel simulation model of the endocrine system of Sprague Dawley rats is presented. It is a simplified mathematical model composed of 3 differential equations and 8 parameters that have been determined and validated with experimental measures of plasma glucose and insulin alone by means of calculus and optimization techniques. The results presented here are a step before the development of a type I diabetic model of Sprague Dawley rats. en
dc.format.extent 188 - 199 es
dc.language es es
dc.subject Mathematical modeling es
dc.subject Diabetes Mellitus es
dc.subject In silico rat es
dc.subject Experimental Data es
dc.title A new minimal mathematical model of the endocrine system of normal rats validated against experimental data en
dc.type Objeto de conferencia es
sedici.identifier.issn 1853-1881 es
sedici.creator.person Campetelli, G. es
sedici.creator.person Lombarte, M. es
sedici.creator.person Rigalli, A. es
sedici.creator.person Basualdo, M. S. es
sedici.subject.materias Ciencias Informáticas es
sedici.description.fulltext true es
mods.originInfo.place Sociedad Argentina de Informática e Investigación Operativa es
sedici.subtype Objeto de conferencia es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
sedici.date.exposure 2011-08
sedici.relation.event II Congreso Argentino de Informática y Salud (CAIS 2011) (XL JAIIO, Córdoba, 29 de agosto al 2 de septiembre de 2011) es
sedici.description.peerReview peer-review es


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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)