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dc.date.accessioned 2022-02-24T15:46:28Z
dc.date.available 2022-02-24T15:46:28Z
dc.date.issued 2004-12
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/131639
dc.description.abstract The work reported here describes the application of the optical technique known as dynamic speckle interferometry to evaluate the motility of nematode parasites exposed to different anthelmintic drugs. This technique, a well proven tool for assessing the time evolution of different phenomena, is here successfully used to quantify parasite motility in pharmacodynamic assays. The characterization of the pharmacological properties of anthelmintic drugs is critical to optimize their use in parasite control. Besides, the evaluation of nematode motility is a relevant indicator of the pharmacodynamic effect of anthelmintic drugs. The application of this approach to study the motility of Haemonchus contortus (used as a model of nematode parasites) larvae exposed to different drugs is presented, showing its usefulness. en
dc.format.extent 694-699 es
dc.language en es
dc.subject Parasites es
dc.subject Pharmacodynamics es
dc.subject Speckle es
dc.title Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility en
dc.type Articulo es
sedici.identifier.other doi:10.1007/s00249-004-0413-4 es
sedici.identifier.other pmid:15133648 es
sedici.identifier.issn 0175-7571 es
sedici.identifier.issn 1432-1017 es
sedici.creator.person Pomarico, J. A. es
sedici.creator.person Di Rocco, Héctor Oscar es
sedici.creator.person Alvarez, L. es
sedici.creator.person Lanusse, Carlos E. es
sedici.creator.person Mottier, L. es
sedici.creator.person Saumell, C. es
sedici.creator.person Arizaga, Ricardo Augusto es
sedici.creator.person Rabal, Héctor Jorge es
sedici.creator.person Trivi, Marcelo Ricardo es
sedici.subject.materias Ingeniería es
sedici.subject.materias Ciencias Exactas es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ingeniería es
mods.originInfo.place Centro de Investigaciones Ópticas es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle European Biophysics Journal es
sedici.relation.journalVolumeAndIssue vol. 33, no. 8 es


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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)