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dc.date.accessioned 2022-03-28T15:43:20Z
dc.date.available 2022-03-28T15:43:20Z
dc.date.issued 2003
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/133387
dc.description.abstract An autocrine/paracrine mechanism is triggered by stretching the myocardium. This mechanism involves the release of angiotensin II (Ang II), the release/increased formation of endothelin (ET), the activation of the Na+/H+ exchanger (NHE), the increase in intracellular Na+ concentration ([Na+]i), and the increase in the Ca2+ transient that underlies the so called slow force response (SFR) to stretch. This autocrine/paracrine mechanism could explain how a change in afterload alters cardiac contractility as was reported by Anrep in 1912. en
dc.format.extent 37-48 es
dc.language es es
dc.publisher Springer es
dc.subject myocardial stretch es
dc.subject Na+/Ca2+ exchange es
dc.subject angiotensin II es
dc.subject endothelin hypertrophy es
dc.title Stretch-Elicited Autocrine/Paracrine Mechanism in the Heart en
dc.type Libro es
sedici.identifier.other doi:10.1007/978-1-4615-0347-7_3 es
sedici.identifier.issn 1389-1774 es
sedici.identifier.isbn 978-1-4615-0347-7 es
sedici.creator.person Cingolani, Horacio Eugenio es
sedici.creator.person Pérez, Néstor Gustavo es
sedici.creator.person Camilión de Hurtado, María Cristina es
sedici.subject.materias Medicina es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ciencias Médicas es
sedici.subtype Capitulo de libro es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/


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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)