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dc.date.accessioned 2022-04-06T19:11:28Z
dc.date.available 2022-04-06T19:11:28Z
dc.date.issued 2020-12-23
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/134045
dc.description.abstract The study of novel mechanisms of action of vanadium compounds is critical to elucidating the role and importance of these kinds of compounds as antitumor and antimetastatic agents. This work deals with in silico and in vitro studies of one clioquinol oxidovanadium(IV) complex [VO(clioquinol)2], VO(CQ)2, and its regulation of FAK. In particular, we focus on elucidating the relationship of the FAK inhibition, MMP activity and antimetastatic effects of the complex in human bone cancer cells. en
dc.format.extent 1931-1940 es
dc.language en es
dc.subject vanadium compounds es
dc.subject human osteosarcoma cancer cells es
dc.title In silico and in vitro analysis of FAK/MMP signaling axis inhibition by VO-clioquinol in 2D and 3D human osteosarcoma cancer cells en
dc.type Articulo es
sedici.identifier.other doi:10.1039/d0mt00176g es
sedici.identifier.other pmid:33107537 es
sedici.identifier.issn 1756-591X es
sedici.identifier.issn 1756-5901 es
sedici.creator.person Balsa, Lucía Mariana es
sedici.creator.person Quispe Castillo, Patricia Araceli es
sedici.creator.person Baran, Enrique José es
sedici.creator.person Lavecchia, Martín José es
sedici.creator.person León, Ignacio Esteban es
sedici.subject.materias Salud es
sedici.subject.materias Química es
sedici.description.fulltext true es
mods.originInfo.place Centro de Química Inorgánica es
sedici.subtype Preprint es
sedici.rights.license Creative Commons Attribution 4.0 International (CC BY 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Metallomics es
sedici.relation.journalVolumeAndIssue vol. 12, no. 12 es


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Creative Commons Attribution 4.0 International (CC BY 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution 4.0 International (CC BY 4.0)