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dc.date.accessioned | 2022-07-06T14:44:42Z | |
dc.date.available | 2022-07-06T14:44:42Z | |
dc.date.issued | 1978 | |
dc.identifier.uri | http://sedici.unlp.edu.ar/handle/10915/139001 | |
dc.description.abstract | The effect of catecholamines and adrenergic blocking agents on the oxidative desaturation of linoleic acid in rat liver microsomes was studied. Epinephrine (1 mg/kg/body weight) produced a significant decrease on the conversion of [1-14C]linoleic acid to gamma-linolenic acid. The effect of epinephrine was blocked by single injections of the beta blockers propranolol (10 mg/kg body weight) or dichloroisoproterenol 30 min before the hormone treatment. Isoproterenol (100 microgram/kg body weight) produced a significant decrease on the activity of the linoleyl-CoA desaturase. The effect of the catecholamines was postulated to be mediated through beta receptors by an enhancement of the intracellular levels of cyclic AMP. | en |
dc.format.extent | 649-652 | es |
dc.language | en | es |
dc.subject | blocking agent | es |
dc.subject | linoleic acid | es |
dc.subject | rat liver | es |
dc.subject | hormone treatment | es |
dc.title | Effect of catecholamines and β-blockers on linoleic acid desaturation activity | en |
dc.type | Articulo | es |
sedici.identifier.other | doi:10.1007/bf02533740 | es |
sedici.identifier.other | pmid:27520107; 31543 | es |
sedici.identifier.issn | 0024-4201 | es |
sedici.identifier.issn | 1558-9307 | es |
sedici.creator.person | Tacconi de Gómez Dumm, Irma Nelva | es |
sedici.creator.person | Tacconi de Alaniz, María Josefa | es |
sedici.creator.person | Brenner, Rodolfo Roberto | es |
sedici.subject.materias | Medicina | es |
sedici.subject.materias | Bioquímica | es |
sedici.description.fulltext | true | es |
mods.originInfo.place | Facultad de Ciencias Médicas | es |
sedici.subtype | Articulo | es |
sedici.rights.license | Creative Commons Attribution 4.0 International (CC BY 4.0) | |
sedici.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
sedici.description.peerReview | peer-review | es |
sedici.relation.journalTitle | Lipids | es |
sedici.relation.journalVolumeAndIssue | vol. 13, no. 10 | es |