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dc.date.accessioned | 2022-07-14T17:23:55Z | |
dc.date.available | 2022-07-14T17:23:55Z | |
dc.date.issued | 1980-09 | |
dc.identifier.uri | http://sedici.unlp.edu.ar/handle/10915/139565 | |
dc.description.abstract | Perfusion of the isolated rat heart at constant heart rate and coronary flow with the inhibitor of cyclic nucleotide phosphodiesterase, pentoxifylline (10(-4) moles/l), produced no significant effect on the maximum rate and the peak of contraction, but increased the maximum rate of relaxation. cAMP level and cAMP-dependent protein kinase activity were increased in the absence of changes in cGMP. The results were identical in hearts of reserpinized rats. | en |
dc.format.extent | 1088-1090 | es |
dc.language | en | es |
dc.subject | Nucleotide | es |
dc.subject | Protein Kinase | es |
dc.subject | Kinase Activity | es |
dc.subject | Maximum Rate | es |
dc.subject | Phosphodiesterase | es |
dc.title | The mechanical and biochemical effects of pentoxifylline on the perfused rat heart | en |
dc.type | Articulo | es |
sedici.identifier.other | doi:10.1007/bf01965986 | es |
sedici.identifier.other | pmid:6252042 | es |
sedici.identifier.issn | 0014-4754 | es |
sedici.identifier.issn | 1420-9071 | es |
sedici.identifier.issn | 1420-682x | es |
sedici.creator.person | Vittone, Leticia Beatriz | es |
sedici.creator.person | Chiappe, Liliana Eusebia | es |
sedici.creator.person | Argel, María Isabel | es |
sedici.creator.person | Cingolani, Horacio Eugenio | es |
sedici.creator.person | Chiappe de Cingolani, Gladys Ethel | es |
sedici.subject.materias | Medicina | es |
sedici.description.fulltext | true | es |
mods.originInfo.place | Centro de Investigaciones Cardiovasculares | es |
sedici.subtype | Articulo | es |
sedici.rights.license | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | |
sedici.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
sedici.description.peerReview | peer-review | es |
sedici.relation.journalTitle | Experientia | es |
sedici.relation.journalVolumeAndIssue | vol. 36, no. 9 | es |