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dc.date.accessioned 2022-08-10T20:05:20Z
dc.date.available 2022-08-10T20:05:20Z
dc.date.issued 2021-08-18
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/140394
dc.description.abstract Imazethapyr is an herbicide that is used in a variety of crops worldwide, including soybean and corn. The aim of the present study was to evaluate the biomarkers responses of adult Leptodactylus latinasus exposed to the formulation Pivot® H (10.59% imazethapyr) in the laboratory at concentrations and under conditions that simulate two potential field exposure scenarios: an immersion in field runoff (Scenario 1: 10 mg/L) and a direct exposure to the droplets emitted by spray noozles (Scenario 2: 1000 mg/L). In both scenarios, the experimental procedure involved completely immersing the frogs over a period of 15 s. Different endpoints were evaluated at several ecotoxicological levels 48 and 96 h after the herbicide exposure. These included individual (biometric indices and behavior alterations), histological (liver pigments and lesions), biochemical (catalase, glutathione system and cholinesterase activities) and genotoxic effects (micronuclei induction and nuclear abnormalities). Forty-eight hours after imazethapyr exposure, frogs submitted to Scenario 1 presented an inhibition of liver glutathione-S-transferase activity, whereas histological alterations and increased hepatic cholinesterase levels were observed in frogs exposed under Scenario 2. Ninety-six hours after exposure to the imazethapyr formulation, frogs from the Scenario 1 treatment presented a decrease in liver melanin and hemosiderin, increased hepatic catalase activity and micronuclei induction. For their part, frogs exposed to Scenario 2 presented a decrease in the hepatosomatic index, an increase in liver alterations, melanin reduction and micronuclei induction. The multivariate analysis enables correlations to be made between biomarkers of different organizational level in exposed anurans. Our result indicates that real exposure to imazethapyr formulations under field conditions may pose a risk to Leptodactylus latinasus populations living in the agroecosystems. en
dc.format.extent 492-506 es
dc.language en es
dc.subject biomarkers responses es
dc.subject toxic effect es
dc.subject frogs es
dc.title Multiple Level Effects of Imazethapyr on Leptodactylus Latinasus (Anura) Adult Frogs en
dc.type Articulo es
sedici.identifier.other doi:10.1007/s00244-021-00880-w es
sedici.identifier.other pmid:34406426 es
sedici.identifier.issn 1432-0703 es
sedici.identifier.issn 0090-4341 es
sedici.creator.person Pérez Iglesias, Juan Manuel es
sedici.creator.person Zácari Fanali, Lara es
sedici.creator.person Franco Belussi, Lilian es
sedici.creator.person Natale, Guillermo Sebastián es
sedici.creator.person Oliveira, C. de es
sedici.creator.person Brodeur, Julie Céline es
sedici.creator.person Larramendy, Marcelo Luis es
sedici.subject.materias Ciencias Naturales es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ciencias Naturales y Museo es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution 4.0 International (CC BY 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Archives of Environmental Contamination and Toxicology es
sedici.relation.journalVolumeAndIssue vol. 81, no. 3 es

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Creative Commons Attribution 4.0 International (CC BY 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution 4.0 International (CC BY 4.0)