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dc.date.accessioned 2023-08-14T17:56:10Z
dc.date.available 2023-08-14T17:56:10Z
dc.date.issued 2022
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/156300
dc.description.abstract Entomopathogenic fungi are extensively used for the control of insect pests worldwide. Among them, Beauveria bassiana (Ascomycota: Hypocreales) produce a plethora of toxic secondary metabolites that either facilitate fungal invasion or act as immunosuppressive compounds. These toxins have different chemical natures, such as nonribosomal peptides and polyketides. Even though their precise role is poorly understood, they are usually linked to virulence. These fungal secondary metabolites are produced by the expression of gene clusters encoding the various proteins needed for their biosynthesis. Each cluster includes synthetases for nonribosomal peptides (NRPS), polyketides (PKS), or hybrid NRPS–PKS genes. The aim of this review is to summarize the information available from transcriptomics and quantitative PCR studies related to the expression of B. bassiana NRPS and PKS genes inside different insects as the infection progresses; as for the host immune response, to help understand the mechanisms that these toxins trigger as virulence factors, antimicrobials, or immunosuppressives within the context of a fungus–insect interaction. en
dc.language en es
dc.subject entomopathogenic fungi es
dc.subject virulence es
dc.subject nonribosomal peptides (NRPS) es
dc.subject polyketides (PKS) es
dc.title The entomopathogenic fungus Beauveria bassiana shows its toxic side within insects: expression of genes encoding secondary metabolites during pathogenesis en
dc.type Articulo es
sedici.identifier.other https://doi.org/10.3390/jof8050488 es
sedici.identifier.issn 2309-608X es
sedici.creator.person Pedrini, Nicolás es
sedici.subject.materias Biología es
sedici.description.fulltext true es
mods.originInfo.place Instituto de Investigaciones Bioquímicas de La Plata es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution 4.0 International (CC BY 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Journal of Fungi es
sedici.relation.journalVolumeAndIssue vol. 8, no. 5 es


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Creative Commons Attribution 4.0 International (CC BY 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution 4.0 International (CC BY 4.0)