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dc.date.accessioned 2012-06-14T19:31:33Z
dc.date.available 2012-06-14T19:31:33Z
dc.date.issued 2012
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/18259
dc.description.abstract The antihyperglycaemic effect of Casearia sylvestris aqueous extract (CS) and its flavonoidic fraction using in vivo models in streptozotocin-induced diabetic rats was evaluated. CS (500 mg/kg) reduced blood glucose in rats three weeks after a single oral dose. The blood glucose significantly decreased in a test of tolerance to insulin. Phytochemical investigation on TLC, HPLC-DAD and NMR spectral analysis of extract and fractions confirmed the presence of flavonoids. These results direct the hypothesis that CS improves glucose metabolism by reducing insulin resistance, and it may be useful for the treatment of type 2 diabetes. es
dc.format.extent 421-426 es
dc.language en es
dc.subject antihyperglycemic effect; casearia sylvestris; flavonoid es
dc.subject Farmacología es
dc.subject Diabetes Mellitus Tipo 2 es
dc.title Antihyperglycemic effect of casearia sylvestris leaves extract in streptozotocin induced diabetic rats es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/31/3/LAJOP_31_3_1_11.pdf es
sedici.identifier.issn 0326-2383 es
sedici.creator.person Buccioli, Paulo T. es
sedici.creator.person Bortolin, Raul H. es
sedici.creator.person Furini, Gleison T. es
sedici.creator.person Cincotto, Danielli U. es
sedici.creator.person Sousa, Janaína H. es
sedici.creator.person França, Suzelei C. es
sedici.creator.person Oliveira, Luciana es
sedici.creator.person Pereira, Paulo S. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Articulo es
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Latin American Journal of Pharmacy
sedici.relation.journalVolumeAndIssue vol. 31, no. 3


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