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dc.date.accessioned 2012-08-27T15:32:20Z
dc.date.available 2012-08-27T15:32:20Z
dc.date.issued 2012
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/20182
dc.description.abstract The aim of the present study was to establish a method for the determination of folic acid and related substances content in dispersible tablets. Method: A Shim-pack VP-ODS C18 reversed phase column (4.6 mm × 250 mm) was used. The mobile phase consisted of methanol-phosphate buffer (20:80) with a pH of 6.3.The flow rate was 1.0 mL/min, and the detection wavelength was 277nm and the column temperature was 30 °C. Results: The calibration curve was linear in the range of 5~150 μg/mL (r = 0.9998) for folic acid. The minimal detection limit was 99.08 %, n = 9 and the related substances were well separated. This method resulted to be convenient, accurate, selective and reliable, and can be applied for the quality control of folic acid. en
dc.format.extent 555-560 es
dc.language en es
dc.subject Content determination en
dc.subject Ácido Fólico es
dc.subject Folic acid and related substances en
dc.subject Métodos es
dc.subject HPLC en
dc.title Determination of folic acid and its related substances of the ferrous fumarate and folic acid dispersible tablet by HPLC en
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/31/4/LAJOP_31_4_1_10.pdf es
sedici.identifier.issn 0326-2383
sedici.creator.person Chen, Qiaoyun es
sedici.creator.person Liu, Yang es
sedici.creator.person Luo, Y.H. es
sedici.creator.person Luo, M. es
sedici.creator.person Luo, L.Y. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Articulo es
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 31, no. 4 es


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