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dc.date.accessioned 2012-08-28T15:40:32Z
dc.date.available 2012-08-28T15:40:32Z
dc.date.issued 2012
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/20229
dc.description.abstract The validation of a microbiological assay, applying agar diffusion method for determination of the active of cefuroxime in power for injection, is described. Using a strain of Micrococcus luteus ATCC 9341 as the test organism, cefuroxime was measured in concentrations ranging from 30.0 to 120.0 μg/mL. The method validation showed that it is linear (r = 0.9999), precise (relative standard deviation = 0.37 %) and accurate (it measured the added quantities). Microbiological assay is satisfactory for quantitation of cefuroxime in powder for injection and the validity of the proposed bioassay, which is a simple and a useful alternative methodology for cefuroxime determination in routine quality control. en
dc.format.extent 746-750 es
dc.language en es
dc.subject Cefuroxime en
dc.subject Cefuroxima es
dc.subject Cefalosporinas es
dc.subject Cephalosporins en
dc.subject Control de Calidad es
dc.subject Microbiological assay en
dc.subject Quality control en
dc.subject Validation en
dc.title Validation of microbiological assay for determination of cefuroxime in injectable preparations en
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/31/5/LAJOP_31_5_2_2.pdf es
sedici.identifier.issn 0326-2383
sedici.creator.person Vieira, Daniela C.M. es
sedici.creator.person Ricarte, Patrícia C. es
sedici.creator.person Salgado, Hérida R.N. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 31, no. 5 es


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