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dc.date.accessioned 2019-05-29T16:38:43Z
dc.date.available 2019-05-29T16:38:43Z
dc.date.issued 2015
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/75587
dc.description.abstract A pH-sensitive blend of polyurethane (PU) and poly(2-(diethyl amino)ethyl methacrylate (PDEA) with good film‑forming capacity was prepared from the corresponding aqueous dispersions. The polymer matrix was first characterized by using FTIR, DSC, water vapor transmission and water swelling capacity at different pHs. The drug release profile of films was evaluated using a vertical Franz Cell and theophylline as model drug. The water swelling degree increases from 54 to 180% when the pH of the medium is changed from 6 to 2, demonstrating the pH-responsive behavior of the film. The in-vitro release studies indicate that an anomalous transport mechanism governs the theophylline release. en
dc.format.extent 336-343 es
dc.language en es
dc.subject poliuretanos, sistemas de liberación de medicamentos, teofilina es
dc.subject polyurethanes, drug delivery systems, stimuli-sensitive polymers, swelling, theophylline en
dc.title Polyurethane/Poly(2-(Diethyl Amino)Ethyl Methacrylate) blend for drug delivery applications en
dc.type Articulo es
sedici.identifier.other http://hdl.handle.net/11746/5757
sedici.identifier.other https://doi.org/10.1590/0104-1428.1716
sedici.creator.person Echeverría, María Gabriela es
sedici.creator.person Pardini, Oscar Ricardo es
sedici.creator.person Debandi, María Valeria es
sedici.creator.person François, Nora Judit es
sedici.creator.person Daraio, Marta Edith es
sedici.creator.person Amalvy, Javier Ignacio es
sedici.subject.materias Ingeniería Química es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ingeniería es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Polímeros: Ciência e Tecnologia es
sedici.relation.journalVolumeAndIssue vol. 25. no. 4 es


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Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)