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dc.date.accessioned 2010-04-07T17:03:45Z
dc.date.available 2010-04-07T03:00:00Z
dc.date.issued 2010 es
dc.identifier.uri http://hdl.handle.net/10915/7906
dc.description.abstract The present study evaluated novel polymer mixtures prepared by spray drying of an aqueous dispersion of moth bean starch with Carbopol 934P and HPMC K4M for to be used as platform for peroral mucoadhesive drug delivery. 32 factorial designs were employed to evaluate influence of different concentrations of hydrophilic polymers i.e. Carbopol 934P and HPMC K4M with constant concentration of moth bean starch on the drug release as well as in vitro adhesion time. All the formulations were studied for physical evaluation i.e. hadness, friability, content uniformity, drug-excipient compatibility as well as stability study. Two formulations F1 and F4 out of nine containing low amount of synthetic polymer exhibited desirable in vitro mucoadhesion time >8 h and drug release >90 % in controlled manner. es
dc.format.extent p. 279-283 es
dc.language en es
dc.title Development and evaluation of acyclovir mucoadhesive tablet using a novel starch based platform es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/29/2/LAJOP_29_2_2_3.pdf es
sedici.creator.person Singh, Akhilesh V. es
sedici.creator.person Nath, Lila K. es
sedici.subject.materias Farmacia es
sedici.subject.descriptores Farmacología es
sedici.subject.descriptores Evaluación de drogas es
sedici.subject.keyword acyclovir; Carbopol 934P; HPMC K4M; moth bean starch; mucoadhesive tablet es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001392 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 29, no. 2 es


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