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dc.date.accessioned 2010-05-03T17:47:14Z
dc.date.available 2010-05-03T03:00:00Z
dc.date.issued 2010 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/7914
dc.description.abstract New rapid first-derivative spectrophotometric (UVDS) and a stability-indicating high performance liquid chromatographic (HPLC) methods were developed, validated and successfully applied in the analysis of loratadine (LT) in tablets and syrups. In the UVDS method, 0.1 M HCl was used as solvent. The measurements were made at 312.4 nm in the first order derivative spectra. The HPLC method was carried out on a RP-18 column with a mobile phase composed of methanol-water-tetrahydrofuran (50:30:20, v/v/v). UV detection was made at 247 nm. For HPLC methods the total analysis time was <3min, adequate for routine quality control of tablets and syrups containing loratadine. es
dc.format.extent 325-332 es
dc.language en es
dc.subject Farmacología es
dc.subject assay methods; first-derivative spectrophotometry; liquid chromatography; loratadine es
dc.subject Cromatografía es
dc.title New rapid Derivative spectrophotometric and chromatographic methods for assay of loratadine in tablets and syrups es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/29/3/LAJOP_29_3_1_1.pdf es
sedici.creator.person Nogueira, Nayane M. es
sedici.creator.person Alves, João M. P. es
sedici.creator.person Santoro, Maria Ines Rocha Miritello es
sedici.creator.person Singh, Anil K. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Articulo es
sedici.description.peerReview peer-review es
sedici2003.identifier ARG-FARM-ART-0000001400 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 29, no. 3 es


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