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dc.date.accessioned 2010-09-23T15:19:58Z
dc.date.available 2010-09-23T03:00:00Z
dc.date.issued 2010 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8004
dc.description.abstract This study evaluates the in vitro anti-trichomonads activity of a saponin enriched fraction (MSF) obtained from the fruits of Ilex paraguariensis A. St. Hil. (Aquifoliaceae). The MSF showed better anti-trichomonads activity than polysorbate and tyloxapol. A similar activity was obtained for quillaja saponins, but this fraction presented the highest cytotoxicity to mammalian cells as follows: quillaja > tyloxapol > polysorbate 80 > MSF. Neither the co-addition of MSF and metronidazole (MTZ) nor the pretreatment of the trophozoites with MSF prior to the addition of MTZ elicited a significant effect on MTZ activity. es
dc.format.extent 914-918 es
dc.language en es
dc.subject cytotoxicity; Ilex paraguariensis; metronidazole; quillaja; saponins es
dc.subject Farmacología es
dc.subject Citotoxicidad es
dc.subject Plantas medicinales es
dc.title Anti-trichomonas vaginalis activity of saponins from Ilex paraguariensis ("mate") fruits es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_1_9.pdf es
sedici.creator.person Treter, Janine es
sedici.creator.person Peixoto, Maria P. G. es
sedici.creator.person Giordani, Raquel B. es
sedici.creator.person Holz, Carine L. es
sedici.creator.person Roehe, Paulo M. es
sedici.creator.person Tasca, Tiana es
sedici.creator.person González Ortega, George es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Articulo es
sedici.description.peerReview peer-review es
sedici2003.identifier ARG-FARM-ART-0000001491 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 29, no. 6 es


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