Upload resources

Upload your works to SEDICI to increase its visibility and improve its impact


Show simple item record

dc.date.accessioned 2010-09-27T14:26:01Z
dc.date.available 2010-09-27T03:00:00Z
dc.date.issued 2010
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8021
dc.description.abstract The high incidence of diarrhea in the population demands a search for new therapeutic options and easy access, mainly from plant-based sources. Leaves and bark of Guazuma ulmifolia Lam. (Sterculiaceae) are popularly employed against diarrhea. However, no information was found in the literature about this supposed property of the drug. In this study we evaluated in vivo antidiarrheal activity of stem bark extracts from G. ulmifolia in mice, and in vitro antimicrobial activity against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Salmonella sp., Shigella flexneri, and Pseudomonas aeruginosa by using the microdilution method. The n-BuOH semipurified fraction (GU#3) significantly reduced intestinal motility. The extracts did not show antimicrobial activity. G. ulmifolia Lam. had non-specific antidiarrheal, and antimotility activity in the experimental models studied, and could be used as an alternative treatment for non-infectious diarrhea. en
dc.format.extent 1024-1028 es
dc.language en es
dc.subject antidiarrheal activity; antimicrobial screening; condensed tannins; Guazuma ulmifolia; sterculiaceae es
dc.subject Farmacología es
dc.subject Plantas medicinales es
dc.subject Evaluación de drogas es
dc.subject Extractos de plantas es
dc.subject Enfermedades gastrointestinales es
dc.title Antidiarrheal activity of Guazuma ulmifolia Lam. (Sterculiaceae) en
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_6.pdf es
sedici.creator.person Michelin, Daniele C. es
sedici.creator.person Almeida, Glalber C. de es
sedici.creator.person Galina, Karen Janaina es
sedici.creator.person Lopes, Gisely C. es
sedici.creator.person Nakamura, Celso Vataru es
sedici.creator.person Dias Filho, Benedito Prado es
sedici.creator.person Ueda Nakamura, Tânia es
sedici.creator.person Salgado, Hérida R.N. es
sedici.creator.person Mello, João Carlos Palazzo de es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001508 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 29, no. 6 es

Download Files

This item appears in the following Collection(s)