In vitro antioxidant and in vivo anti-inflammatory potential of crude non-alkaloid fractions from fritillaria ussuriensis maxim

Abstract

The present study was conducted to evaluate the antioxidant and anti-inflammatory effects of the ethanol extracts (PBE) and the non-alkaloid fractions, the crude saponin extract (CSE) and the crude flavonoids extract (CFE), of Fritillaria ussuriensis Maxim (PB). The antioxidant activity of PB extracts decreased in the order: CFE >CSE > PBE. All the administered groups produced significant anti-inflammatory effects on the three animal models. The results demonstrated that the different fractions of PB have different responses with different antioxidant methods and anti-inflammation animal models. CSE showed the best antioxidant and anti-inflammatory activities and CFE and PBE followed.