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dc.date.accessioned 2011-03-11T18:56:46Z
dc.date.available 2011-03-11T03:00:00Z
dc.date.issued 2011 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8123
dc.description.abstract A novel compounds of 2-{[3-(trifluoromethyl) phenyl] amino} N, N'-bis (aryl) pyridine-3-carboximidamide (PJS1-PJS6) were synthesized by condensation of niflumic acid with aromatic amines using most reactive Lewis reagent: polyphosphoric acid trimethyl silyl ester (PPSE). These compounds were characterized by IR, 1H-NMR, HRMS-FAB and elemental analysis and evaluated for anti-inflammatory activity using carrageenin- induced rat paw oedema method. Compound PJS 5 showed significant activity exhibiting comparable reduction in edema. es
dc.format.extent 193-196 es
dc.language en es
dc.subject anti-inflammatory activity; niflumic acid; polyphosphoric acid trimethyl silyl ester (PPSE) es
dc.subject Agentes Antiinflamatorios es
dc.title Synthesis and anti-inflammatory activity of 2-{[3-(trifluoromethyl) phenyl] amino} N, N'-bis (aryl) pyridine-3-carboximidamide es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_2_7.pdf es
sedici.creator.person Shirote, Pramodkumar J. es
sedici.creator.person Bhatia, Manish S. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001610 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 30, no. 1 es


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