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dc.date.accessioned 2011-04-07T19:57:25Z
dc.date.available 2011-04-07T03:00:00Z
dc.date.issued 2011 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8145
dc.description.abstract In this study, methanol extracts from the leaf and stem of Dolichandrone spathacea (L.f) K. Schum., a lesser-known local mangrove tree species, was evaluated using disc diffusion and minimum inhibitory concentration (MIC) value determination assays against six strains of local MRSA clinical isolates and one ATCC MRSA reference strain. The stem extract exhibited a higher zone of inhibition as compared with the leaf extract against the tested isolates. Further qualitative evaluation of the stem extract showed MIC values between 1.25 to 1.88 mg/ml against three selected MRSA clinical isolates. Phytochemical screening revealed that the triterpene and saponin compounds might be responsible for the better inhibitory activity from the stem extract as compared to the leaf extract. This study is the first report of the phytochemical screening and the inhibitory activity of D. spathacea leaves and stems methanolic extracts against MRSA clinical isolates. es
dc.format.extent 359-362 es
dc.language en es
dc.subject dolichandrone spathacea; inhibitory potential; methicillin-resistant staphylococcus aureus (MRSA); phytochemical screening es
dc.subject Extractos Vegetales es
dc.subject Técnicas de Química Analítica es
dc.title Inhibitory potential against methicillin-resistant staphylococcus aureus (MRSA) of Dolichandrone spathacea, a mangrove tree species of Malaysia es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_2_2.pdf es
sedici.creator.person Saiful, Azmi J. es
sedici.creator.person Mastura, Mohtar es
sedici.creator.person Mazurah, Mohamed I. es
sedici.creator.person Nuziah, Hashim es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001632 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 30, no. 2 es

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