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dc.date.accessioned 2011-04-27T14:10:39Z
dc.date.available 2011-04-27T03:00:00Z
dc.date.issued 2011 es
dc.identifier.uri http://hdl.handle.net/10915/8177
dc.description.abstract Studies were carried out on the rhizome of Lasia spinosa (L.). The petroleum ether, ethyl acetate and the methanolic extract revealed moderate activities against Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans, Aspergillus niger and Vibrio parahemolyticus test organisms. The crude extracts and purified compound, meridinol (1) were screened for antimicrobial activity against a wide range of gram-positive and gram-negative bacteria and fungi by the disc diffusion method. The cytotoxic potential of the extractives and meridinol was also determined by using brine shrimp lethality bioassay, where the extractives demonstrated significant cytotoxic activities. The petroleum ether, ethyl acetate, methanol extracts, one column fraction and compound 1 demonstrated LC90 of 11.22 μg/ml, 12.3 μg/ml, 13.49 μg/ml, 11.57 μg/ml and 15.85 μg/ml, respectively. es
dc.format.extent p. 550-553 es
dc.language en es
dc.title Antimicrobial and cytotoxic activity from Lasia spinosa and isolated lignan es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/30/3/LAJOP_30_3_2_2.pdf es
sedici.creator.person Alam, Fakrul es
sedici.creator.person Haque, Mozammel es
sedici.creator.person Sohrab, Hossain es
sedici.creator.person Monsur, Mohammad A. es
sedici.creator.person Hasan, Choudhury M. es
sedici.creator.person Ahmed, Nuruddin es
sedici.subject.materias Farmacia es
sedici.subject.decs Raíces de la Planta es
sedici.subject.decs Pruebas de Toxicidad es
sedici.subject.keyword antimicrobial activity; araceae; cytotoxicity; Lasia spinosa; meridinol es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001664 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 30, no. 3 es


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