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dc.date.accessioned 2011-04-28T21:29:54Z
dc.date.available 2011-04-28T03:00:00Z
dc.date.issued 2011 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8181
dc.description.abstract Quantitative Structure Activity Relationship (QSAR) studies were carried out for a series of 16 compounds which acts as ligands for PPAR-γ receptor. TSAR software was used to identify the essential structural and physicochemical features for their PPAR-γ agonistic activity by performing multiple regression analysis. Significant correlation coefficients (q² = 0.9178) was obtained. The predicted values are in good agreement with the observed activity, suggesting that the model could be useful in the design of novel, more potent PPAR-γ agonist. es
dc.format.extent 568-570 es
dc.language en es
dc.subject PPAR-γ receptor; QSAR; thiazolidinedione; TSAR software es
dc.subject Análisis Estadístico es
dc.subject Tiazoles es
dc.title Quantitative structure activity relationship studies of some 5-aryl thiazolidine-2, 4-diones as antidiabetic agents es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/30/3/LAJOP_30_3_2_6.pdf es
sedici.creator.person Sonawane, Lalit V. es
sedici.creator.person Bari, Sanjaykumar B. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001668 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 30, no. 3 es


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