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dc.date.accessioned 2011-12-01T11:42:25Z
dc.date.available 2011-12-01T03:00:00Z
dc.date.issued 2011 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8351
dc.description.abstract A simple reversed phase HPLC method was developed for simultaneous estimation of pioglitazone, glibenclamide, and glibenclamide impurities A and B from a combination drug product. The drugs and impurities are well separated using a reverse phase liquid chromatography with C-8 column. The isocratic mobile phase comprising phosphate buffer (pH 5.0): acetonitrile in the ratio of 75:25 (v/v) at 1.0 mL/min flow rate, UV detection at 250 nm, column temperature was maintained at 30 °C and the injection volume was used 150 μL. The proposed method was validated according to the ICH guidelines and proved suitable for routine analysis and quality control testing of these drugs in pharmaceutical preparations. es
dc.format.extent 1639-1643 es
dc.language en es
dc.subject Combinación de Medicamentos es
dc.subject RP-HPLC; pioglitazone; glibenclamide; validation; impurities es
dc.subject Control de Calidad es
dc.subject Cromatografía Liquida es
dc.subject Estudios de Validación es
dc.title Single RP-HPLC method for simultaneous estimation of pioglitazone, glibenclamide and glibenclamide impurities from a combination drug product es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/30/8/LAJOP_30_8_2_3.pdf es
sedici.creator.person Elango, Kuppanagounder Pitchaimuthu es
sedici.creator.person Karunakaran, Kulandaivelu es
sedici.creator.person Navaneethan, Gurusamy es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001838 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 30, no. 8 es


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