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dc.date.accessioned 2011-12-01T12:53:25Z
dc.date.available 2011-12-01T03:00:00Z
dc.date.issued 2011 es
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/8355
dc.description.abstract The methanol extract of the whole plant of Eclipta prostrata and one of its isolated compounds, eclalbasaponin II were administered to alloxan-induced diabetic rats for 28 and 7 consecutive days, respectively. During the study, a potent antidiabetic activity was observed. Blood sugar was significantly (p < 0.001) reduced by E. prostrata extract (300 mg/kg) and eclalbasaponin II (10 mg/kg), as compared to untreated diabetic rats. Analyses of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) showed no significant (p < 0.001) hepatotoxicity by E. prostrata extractive in alloxan-induced diabetic rats when compared to the diabetic control rats. es
dc.format.extent 1656-1660 es
dc.language en es
dc.subject Extractos Vegetales es
dc.subject diabetes es
dc.subject antidiabetic; Eclipta prostrata; saponin; elalbasaponin es
dc.subject Plantas Medicinales es
dc.title Antidiabetic principle from Eclipta prostrata es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/30/8/LAJOP_30_8_2_7.pdf es
sedici.creator.person Rahman, Mohammad S. es
sedici.creator.person Rahman, Mohammed Z. es
sedici.creator.person Begum, Bilkis es
sedici.creator.person Chowdhury, Rasheduzzaman es
sedici.creator.person Islam, Sk. Nazrul es
sedici.creator.person Rashid, Mohammad A. es
sedici.subject.materias Farmacia es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Comunicacion es
sedici2003.identifier ARG-FARM-ART-0000001842 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 30, no. 8 es


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