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dc.date.accessioned 2012-02-01T17:35:47Z
dc.date.available 2012-02-01T03:00:00Z
dc.date.issued 2011 es
dc.identifier.uri http://hdl.handle.net/10915/8397
dc.description.abstract An ultra-performance liquid chromatography/time-of-flight mass spectrometry (UPLC/QTOF/MS) method was established to analyze the saponins in Rhizoma Paridis saponins (RPS) and the constituents in urinary and feces samples. As we know, the constituents of traditional Chinese medicines are very complex and pre-clinical research including metabolism, excretion and pharmacokinetics of herbal medicine components are of great importance in understanding their biological effects and safety. Therefore, deduction of the metabolic and excretive processes of RPS are necessary. As a result, twenty-two original saponins were detected in RPS-treated urinary and feces. Four excreta were observed in rat feces. Therefore, most original saponins and little deglycosylated saponins have been excreted in the rat urine and feces. es
dc.format.extent p. 1927-1933 es
dc.language en es
dc.title Identification of urinary and feces metabolites of Rhizoma Paridis saponins in rats based on ultra high performance liquid chromatography/time-of-flight mass spectrometry (UPLC/Q-TOF/MS) es
dc.type Articulo es
sedici.identifier.uri http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_9.pdf es
sedici.creator.person Wei, Jinchao es
sedici.creator.person Liu, Changxiao es
sedici.creator.person Man, Shuli es
sedici.creator.person Gao, Wenyuan es
sedici.creator.person Wu, Shanshan es
sedici.subject.materias Farmacia es
sedici.subject.decs Cromatografía Liquida es
sedici.subject.decs Fenómenos Metabólicos es
sedici.subject.decs Rizoma es
sedici.subject.decs Saponinas es
sedici.description.fulltext false es
mods.originInfo.place Colegio de Farmacéuticos de la Provincia de Buenos Aires es
sedici.subtype Articulo es
sedici.description.peerReview peer-review es
sedici2003.identifier ARG-FARM-ART-0000001885 es
sedici.relation.journalTitle Latin American Journal of Pharmacy es
sedici.relation.journalVolumeAndIssue vol. 30, no. 10 es

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