Search among the 160957 resources available in the repository
dc.date.accessioned | 2019-10-29T13:28:51Z | |
dc.date.available | 2019-10-29T13:28:51Z | |
dc.date.issued | 2012 | |
dc.identifier.uri | http://sedici.unlp.edu.ar/handle/10915/84283 | |
dc.description.abstract | The goal of this study was to analyse the effect of growth hormone (GH) on catch-up growth of functional facial (splanchnocranial) and neurocranial components in rats with intrauterine growth retardation (IUGR). Wistar rats were divided into the following groups: control (C), sham-operated (SH), IUGR, and IUGR + GH. IUGR was surgically induced and GH was administered between 21 and 60 days of age. Radiographs were obtained at 1, 21, 42, 63, and 84 days of age in order to measure length, width, and height of neurocranium (NL, NW, and NH) and face length, width, and height (FL, FW, and FH). Analysis of variance was perfomed at 1 day of age and a principal components analysis (PCA) at 84 days of age. Neurocranial and facial volumetric indexes were calculated as NVI = 3√NL × NW × NH and FVI = 3√FL × FW × FH, respectively, and adjusted by non-linear regression analysis. On postnatal day 1, there were significant differences between SH and IUGR (P < 0.01). Also, in both genders, final neurocranial volume was similar between SH and IUGR + GH groups, while the IUGR group had the lower value (P < 0.01). Final facial volume was similar among the three groups. In both genders, facial growth rates were SH = IUGR > IUGR + GH (P < 0.01). The first axis of the PCA exhibited size effect and the second axis showed shape effect. Reductions of placental blood flow modify cranial growth. The functional neurocranial and facial components in rats with IUGR presented different recovery strategies through modular behaviour, mainly related to modifications of growth rate as response to GH administration. | en |
dc.format.extent | 710-718 | es |
dc.language | en | es |
dc.subject | Crecimiento | es |
dc.title | Growth of functional cranial components in rats with intrauterine growth retardation after treatment with growth hormone | en |
dc.type | Articulo | es |
sedici.identifier.other | doi:10.1093/ejo/cjr101 | es |
sedici.identifier.other | eid:2-s2.0-84870503514 | es |
sedici.identifier.issn | 0141-5387 | es |
sedici.creator.person | Quintero, Fabián Aníbal | es |
sedici.creator.person | Castro, Luis Eduardo | es |
sedici.creator.person | Luna, María Eugenia | es |
sedici.creator.person | Guimarey, Luis Manuel | es |
sedici.creator.person | Cesani Rossi, María Florencia | es |
sedici.creator.person | Fucini, María Cecilia | es |
sedici.creator.person | Villanueva, Myriam | es |
sedici.creator.person | Prio, Verónica | es |
sedici.creator.person | Oyhenart, Evelia Edith | es |
sedici.subject.materias | Ciencias Veterinarias | es |
sedici.description.fulltext | true | es |
mods.originInfo.place | Instituto de Genética Veterinaria | es |
mods.originInfo.place | Facultad de Ciencias Naturales y Museo | es |
sedici.subtype | Articulo | es |
sedici.rights.license | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | |
sedici.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
sedici.description.peerReview | peer-review | es |
sedici.relation.journalTitle | European Journal of Orthodontics | es |
sedici.relation.journalVolumeAndIssue | vol. 34, no. 6 | es |
sedici.rights.sherpa | * Color: verde* Pre-print del autor: si* Post-print del autor: si* Versión de editor/PDF:no* Condiciones:>>El pre-print sólo puede depositarse antes de la aceptación>>El pre-print debe acompañarse de una declaración establecida (ver enlace)>>El pre-print no debe reemplazarse por el post-print, sino que se enlazará a la versión publicada con una declaración establecida corregida>>Pre-print on author's personal website, employer website, free public server or pre-prints in subject area>>Post-print en el sitio web personal del autor de manera inmediata>>Post-print in Institutional repositories or Central repositories after |