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dc.date.accessioned 2020-04-15T15:44:24Z
dc.date.available 2020-04-15T15:44:24Z
dc.date.issued 2013
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/93439
dc.description.abstract We present the Binary Local Fractal Dimension (LFD) to analyze osteoporosis induced fracture risk with clinical 3D high resolution quantitative computed tomographic (HRCT) images of human vertebrae. We test if LFD parameters provide precise additional information besides bone mineral density (BMD) and standard descriptors of bone quality, for example bone surface ratio (BS/BV). We define a weighted LFD (wLFD) using the ¯R2 of the H¨older exponents. We compare the LFD with standard methods (distance transform, direct secant method and run-length method) on 5 vertebrae × 8 volumes of interest and 5 repeated scans. The wLFD contains the highest direct and BMD-independent precision (R2 = 0.985 and R2 = 0.949), followed by BS/BV (R2 = 0.977 and R2 = 0.920) including low correlation with BMD (wLFD: R2 = 0.704, BS/BV: R2 = 0.814). LFD improves the translation from reference μCT- to clinical HRCT-resolution. In conclusion, LFD provides a strong diagnostic tool to characterize bone quality to predict osteoporosis induced fracture risk. en
dc.format.extent 232-243 es
dc.language en es
dc.subject Binary local fractal dimension es
dc.subject Hölder exponent es
dc.subject HRCT es
dc.subject Qualitative structure parameter es
dc.title Binary Local Fractal Dimension: a Precise Structure Parameter for 3D High Resolution Computed Tomography Images of the Human Spongiosa en
dc.type Objeto de conferencia es
sedici.identifier.issn 1850-2806 es
sedici.creator.person Thomsen, Felix es
sedici.creator.person Peña, Jaime es
sedici.creator.person Bastgen, Jan es
sedici.creator.person Hoffmann, Beata es
sedici.creator.person Frieling, Isolde es
sedici.creator.person Glüer, Claus-C. es
sedici.creator.person Delrieux, Claudio es
sedici.subject.materias Ciencias Informáticas es
sedici.description.fulltext true es
mods.originInfo.place Sociedad Argentina de Informática e Investigación Operativa es
sedici.subtype Objeto de conferencia es
sedici.rights.license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/
sedici.date.exposure 2013-09
sedici.relation.event XIV Argentine Symposium on Technology (AST) - JAIIO 42 (2013) es
sedici.description.peerReview peer-review es


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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)