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dc.date.accessioned 2020-06-10T13:28:52Z
dc.date.available 2020-06-10T13:28:52Z
dc.date.issued 2018-12
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/97948
dc.description.abstract Fulvia fulva (syn. Cladosporium fulvum, Mycosphaerellaceae) is a dematiaceous fungus that causes tomato leaf mould. It is characterized by its biotrophic lifestyle and the synthesis of the bianthraquinone secondary metabolite, cladofulvin. The aim of the study was to characterize the dark pigment photochemically synthesized by F. fulva and to elucidate its biochemical pathway. We isolated a black pigment from in vitro cultures of the fungus. We determined the pigment to be 1,8-dihydroxynaphthalene (DHN)-melanin based on its chemical and photochemical characteristics, as well as the presence of flaviolin, when fungal reductases were inhibited by tricyclazole. Furthermore, the pks1 gene involved in pigment synthesis has a KS domain already associated with DHN-melanin. Our findings support the relevance of studying melanization in F. fulva. en
dc.format.extent 1-21 es
dc.language en es
dc.subject Biochemistry es
dc.subject Genetics es
dc.subject Microbiology es
dc.subject Molecular biology es
dc.title Identification of an intermediate for 1,8-dihydroxynaphthalene-melanin synthesis in a race-2 isolate of Fulvia fulva (syn. Cladosporium fulvum) en
dc.type Articulo es
sedici.identifier.uri https://ri.conicet.gov.ar/11336/88783 es
sedici.identifier.other https://doi.org/10.1016/j.heliyon.2018.e01036 es
sedici.identifier.other hdl:11336/88783 es
sedici.identifier.issn 2405-8440 es
sedici.creator.person Medina, Rocío es
sedici.creator.person Lucentini, César Gustavo es
sedici.creator.person Franco, Mario Emilio Ernesto es
sedici.creator.person Petroselli, Gabriela es
sedici.creator.person Rosso, Janina Alejandra es
sedici.creator.person Erra Balsells, Rosa es
sedici.creator.person Balatti, Pedro Alberto es
sedici.creator.person Saparrat, Mario Carlos Nazareno es
sedici.subject.materias Biología es
sedici.description.fulltext true es
mods.originInfo.place Centro de Investigaciones de Fitopatología es
mods.originInfo.place Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas es
mods.originInfo.place Instituto de Fisiología Vegetal es
mods.originInfo.place Instituto de Botánica "Dr. Carlos Spegazzini" es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Heliyon es
sedici.relation.journalVolumeAndIssue vol. 4, no. 12 es


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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)