This article described the process used for developing and validating an analysis framework that allows comparing design methodologies for the design creation of Learning Objects (LO) and selecting the one that best meets the needs of teachers based on the needs of a specific educational context. This framework is called MASMDOA (Analysis Framework for the Selection of a Learning Object Design and Deployment Methodology), and it has been applied to a case study where, from a compilation of LO design methodologies used in Ibero-America, one of these methodologies is selected to work in the context of a LO design and production workshop. MASMDOA proved useful for selecting a LO design and deployment methodology that is appropriate for the requirements of an educator in a specific context. To achieve this, MASMDOA proposes a set of criteria that are useful for recommending and characterizing the methodologies to be analyzed and, following a two-phase process, it recommends the methodology that is better suited for the educator's needs. In this paper, we present MASMDOA, the case study to which it was applied, and the results obtained.