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dc.date.accessioned 2022-08-11T17:24:12Z
dc.date.available 2022-08-11T17:24:12Z
dc.date.issued 1988
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/140438
dc.description.abstract The inhibitory effect of vanadate species on the enzymatic activity of bovine copper-zinc superoxide dismutase has been investigated at different pH values and vanadium concentrations. A definite inhibitory effect, clearly related to the main negative charge of each of the vanadate solutions, has been found. The results suggest that the origin of the inhibitory effect may be similar to that found for the phosphate ion, i.e., a diminution of the effectiveness of the substrate electronic guidance mechanism by partial neutralization of the charges close to the active site. Under physiological conditions, the inhibitory effect of vanadate is somewhat smaller than the phosphate. en
dc.format.extent 123-130 es
dc.language en es
dc.subject Copper-zinc superoxide dismutase es
dc.subject vanadium oxoanions es
dc.subject inhibitory effect es
dc.subject effect of main negative charge es
dc.subject comparison with phosphate action es
dc.title The inhibitory effect of vanadium oxoanions on the activity of copper-zinc superoxide dismutase en
dc.type Articulo es
sedici.identifier.other doi:10.1007/bf02917496 es
sedici.identifier.other pmid:2484557 es
sedici.identifier.issn 0163-4984 es
sedici.identifier.issn 1559-0720 es
sedici.creator.person Apella, María Cristina es
sedici.creator.person González, Silvia Nelina es
sedici.creator.person Baran, Enrique José es
sedici.subject.materias Ciencias Exactas es
sedici.description.fulltext true es
mods.originInfo.place Facultad de Ciencias Exactas es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution 4.0 International (CC BY 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Biological trace element research es
sedici.relation.journalVolumeAndIssue vol. 18, no. 1 es


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Creative Commons Attribution 4.0 International (CC BY 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution 4.0 International (CC BY 4.0)