Protooncogene C-myc in buccal mucosa overexpression

Abstract

The superfamily c-myc would be associated with different neoplasms. C-myc is amplified when the cell proliferation index is high. For some epithelial tumors, aggressiveness and risk of metastasis would increase when there is overexpression of c-myc. The objective of this work was to study the amplification and/or overexpression of the protooncogene c-myc in benign proliferative lesions and cancer located in buccal mucosa. Consequently, we analyzed 15 footage samples corresponding to the former and 10 carcinomas corresponding to squamous cells, all HPV, and 10 control samples.