In this article, we present a search technique based on metaheuristics for approximately solving the vehicle routing problem with time windows (VRPTW). The Problem Aware Local Search (PALS) is the metaheuristic selected, which proves to be a powerful technique for solving the DNA Fragment Assembly Problem. PALS performs a trajectory in the search space by improving a single solution using a specific move operator. A detailed description of the algorithmic design points and the operators for the VRPTW are carried out.
Furthermore, preliminary results are shown and analyzed.