Liver Nuclear Lipid Droplets are a dynamic nuclear domain

Abstract

The cell nucleus (N) is a highly compartmentalized organelle characterized by several dynamic domains. In the laboratory it was shown for the first time that nuclear lipid droplets (nLD) are a new class of subnuclear bodies and a nuclear domain where neutral lipids are stored and organized. These droplets would be built up around a hydrophobic core of TAG and CE enriched in oleic acid and surrounded by a monolayer of polar lipids along with C and associated proteins. nLD components represent an exceedingly small proportions of the total cell components.