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Postnatal exposure to a progestin does not prevent uterine adenogenesis in domestic dogs

Document type: Comunicacion

Abstract

To assess the effects of a single supraphysiological postnatal administration of a progestogen on uterine glands in dogs, 10 females were randomly assigned to a medroxyprogesterone acetate 35 mg (MPA; n = 6) or placebo (n = 4) group within the first 24 h of birth. The safety of the treatment was also evaluated. A transient mild clitoris enlargement appeared in MPA-treated females. Microscopic postpubertal uterine assessment revealed the presence of uterine glands in all cases without significant differences in the area occupied by the glands per μm2 of endometrium nor in the height of the uterine epithelium.

General information

Issue date: 2016
Document language: English
Journal: Journal of Veterinary Science; vol. 17, no. 1
Origin: Facultad de Ciencias Veterinarias
Others identifiers: https://doi.org/10.4142%2Fjvs.2016.17.1.111
ISSN: 1976-555X
Pages: 111-113

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Created: 25 de octubre de 2017
Available since: 25 de octubre de 2017
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  • http://sedici.unlp.edu.ar/handle/10915/63180

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    Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)