Effect of the chronic treatment with aqueous extract of Caesalpinia ferrea and Chrysobalanus icaco on the vascular reactivity of diabetic rats

Carvalho, Adriana A.; Menezes, Igor A. C.; Antoniolli, Angelo R.; Santos, Márcio R.V.

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Effect of the chronic treatment with aqueous extract of Caesalpinia ferrea and Chrysobalanus icaco on the vascular reactivity of diabetic rats

Autores: Carvalho, Adriana A. | Menezes, Igor A. C. | Antoniolli, Angelo R. | Santos, Márcio R.V.

2010

Tipo de documento: Comunicacion

Resumen

Caesalpinia ferrea and Chrysobalanus icaco are plants commonly used by the folk medicine for the treatment of diabetes mellitus. In this work, the effects of the chronic treatment with aqueous extracts of C. ferrea (AECF) and C. icaco (AECI) on the vascular reactivity of alloxan-induced diabetic rats were evaluated. In rings of mesenteric artery, AECF and AECI were not able to modify the contractions induced by phenylephrine or relaxations induced by carbachol. However, treatment with AECI was able to prevent the potentiation of the relaxations induced by sodium nitroprusside in diabetic rats. In brief, this study found possible benefits of the treatment with C. icaco on the reactivity vascular of diabetic rats.