Any system interacting with a data base requires modules capable of operating data stored in it. Its development times generally vary between 50 to 60 % of the time used for the application life cycle. The present paper describes the architecture and characteristics of a Framework for the agile generation of Web Applications, called PHP4DB. Its main objectives are to drastically reduce the job time, minimize errors, and tuning, as well as respect a homogeneous interface between each module. These characteristics allow the development team to focus and make emphasis on the tasks particular to the application domain. For a better understanding of its advantages, some of the projects in which the Framework has been used are presented together with the respective analysis of the results obtained.