Chagas is a complex socio-environmental health problem characterised by the dynamic interrelation of different aspects with dimensions of diverse nature (biomedical, epidemiological, sociocultural, political-economic, and others). In other words, Chagas is much more than a disease and, in order to address it, it is essential to understand not only key aspects of the parasite, its routes of transmission, and medical aspects, but also the views of the different actors involved, public policies, the rights of the affected people... Admitting this helps us understand that any answer that seeks to generate contextualised and sustained solutions over time, must include and bring these different dimensions into play.